Drug administration and blood sampling experiments in animals are common practice in scientific research. Here are some common problems researchers can face:

• Injection timing can be different between experimental animals during prolonged drug administration designs leading to extra variables in the experiment.
• Daily injection adds operational complexity and causes stress to the animal.
• Conventional drug administration methods may deliver insufficient dosages to the target areas due to factors such as drug metabolism or physiological barriers like the blood-brain barrier.

You might find yourself thinking: There must be a better way! And Yes there is. Here are 3 sets of solutions for different experimental designs.

Scenario 1: Time/Location Specific Drug Administration and Blood Sampling in Free Moving Animals

Small Animal Vein Catheterization system: Our specifically designed PU catheters can be implanted into the animal’s veins, arteries, bile ducts, etc., allowing for sampling and drug administration via an automated system. The system can be used to perform time or location dependent drug delivery and blood sampling experiments

Scenario 2: Long term Drug Administration

Our Implantable Slow-Release Pump is ideal for drug delivery in long term drug infusion studies. The pump works by principles of osmolarity and slowly releases the drug payload at a constant rate once implanted inside the body. The pump can be implanted to perform subcutaneous or intraperitoneal delivery at a constant flow rate for up to four weeks. Additionally, the pump comes with accessories for long term intracranial infusion in conjunction with a custom built cannula.

Scenario 3: Intracranial Drug Delivery

Applicable Research: Research involving the construction and treatment of disease models, neural circuit studies, and investigations into neural molecular mechanisms.

• The Micro-Drug Administration Cannula is the current gold standard for drug delivery. After implanting the cannula to your desired brain regions, quantitative drug administration can be performed repeatedly at precise timing. RWD Life Sciences offers custom services for single and dual channel cannula systems with adjustable guide and injector length.

• The Micro-Infusion Pump ensures the perfect control of timing and dosage of release in your drug delivery study. The latest high-precision R462 micro-infusion pump from Reward Life Sciences features can be used for both drug delivery and blood sampling. It is suitable for chemical reaction injection experiments, long-term animal drug administration experiments, and other laboratory micro-injection experiments.

• Our Automated Stereotaxic Injection Systems allows for fully automated stereotaxic surgeries with set injection coordinates and dwell times for up to 10 locations. Simply enter your coordinates on our color LCD touchscreen, and our custom software will control the precise electrode movement to complete injections or implant at each location.