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R821 Tricolor Multichannel Fiber Photometry System
R821 Tricolor Multichannel Fiber Photometry System
R821 Tricolor Multichannel Fiber Photometry System-2
R821 Tricolor Multichannel Fiber Photometry System
R821 Tricolor Multichannel Fiber Photometry System
R821 Tricolor Multichannel Fiber Photometry System
R821 Tricolor Multichannel Fiber Photometry System-2
R821 Tricolor Multichannel Fiber Photometry System

R821 Tricolor Multichannel Fiber Photometry System

R821 tricolor multichannel fiber photometry system is compatible with optoelectronics equipment. It has different wavelengths of excited light, 410nm, 470nm or 560nm, of which 410 is used to acquire reference signal and eliminate noise. The system can record signal of green fluorescence indicator like GCaMP and dLight or neurotransmitter probe and red fluorescence indicator like RCaMP, jrGECO1a or neurotransmitter probe.

And also it can be applied to record the neural signal for 9 sites at the same time.

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Overview

The fiber photometry system records changes in the fluorescence intensity of neurons in a specific brain area to reflect neuronal population activity. In the study of neural circuits, the fiber photometry system can perform long-term stable monitoring of the neurons of freely moving animals, and explore the correlation between neural activity and animal behavior.

Fiber Photometry System Applications:

Fiber-Photometry-System-Applications

Highlights of R821 Fiber Photometry System

  • Three kinds of excitation light sources, that are 410nm、470nm and 560nm, are respectively used for excitation of reference, green fluorescence and red fluorescence;
  • Support up to 9 channels, suitable for simultaneous experiment of multiple animals or multiple brain locations;
  • Dual highly sensitive detectors enabling independent and sequential detection to avoid interference of fluorescence excitation and detection, acquiring more accurate signals;
  • Professional acquisition and analysis softwares are flexible and easy to operate with data processing functions available. No matlab programming is required;
  • Supports multiple acquisition modes including continuous acquisition, interval acquisition, acquisition upon trigger, delayed acquisition and timing acquisition;
  • Live display of DeltaF/F acquisition to check scale of signal changes during acquisition;
  • Customized adjustment of output signal parameters, easily trigger and control external excitation equipment to achieve closed-cycle control of excitation and recording;
  • Compatible with optogenetics for recording and stimulation at the same site.

R821 Tricolor Multichannel Fiber Photometry System

Stable Data Acquisition

Fluorescence-Comparison-Fiber-Photometry-System

Fluorescence Comparison

Download R821 Tricolor Multichannel Fiber Photometry System Brochure

Publications

RWD Fiber Photometry Recording System has published nearly 30 research papers in journals such as Nature Neuroscience, Cell Stem Cell, Neuron, Nature Communications, The Journal of Clinical Investigation and other journals. Our list of collected papers includes about 11 research topics such as Learning and Memory, Reward and Addiction, Emotions, Psychiatric Disorders Research, Neurodegenerative Diseases Research, etc.
Download Publications List

Advantages

One-click Graphs

Including fluorescence heatmaps, curve graphs, animal trajectory graphs, etc

Signal Acquisition Sensitivity

Meets the need for weak signal detection at the picowatt level (axons/glia)

Professional Data Analysis

Comprehensive data analysis, with a complete pre-processing process, and event refinement analysis, support for multi-dimensional results and format output

High Integration

The whole machine and software integrated design, built-in optogenetic interface, to achieve the same site stimulation and recording

Stable Performance

Over 500 hours of stable acquisition to meet the needs of sleep and other experiments

Strong Expansion

With 4 input and 4 output digital interface and excitation light combination mode, support for up to 9-channel acquisition

Videos

Successful Cases

Fiber Photometry System-success-case-1.

Journal: Nature Neuroscience

Using fiber photometry to detect the activity of SuM-DG neuronal projections in novel environments

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Fiber Photometry System-success-case-1

Journal: Cell Stem Cell

Using fiber photometry to detect the activity of SuM-DG neuronal projections in AD mice

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Fiber-Photometry-System-success-case

Journal: Neuron

Using fiber photometry to detect dynamic changes in calcium signaling in LDT (GABA) neurons of awake mice under different sensory stimuli

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Ready to Get Started?

We have done fiber photometry system online demo with more than 100 globa customers and got exemplary feedback from them. Welcome to try our free virtual demo to learn how our fiber photometry system can help in advanced neuroscience research.

Request Free Demo
Request Fiber Photometry System Free Demo

Clients Say

Combination with Electro Stimulation

The RWD fiber photometry can meet the requirements of complex procedures (in combination with electro stimulation). The software operation and data analysis are very simple, we are very satisfied with this device.

Institute-of-Pharmacology-Polish-Academy-of-Science

Institute of Pharmacology Polish Academy of Science

Easy to Set up and Operate

We are studying neural circuit mechanisms of animal behaviors in health and disease, with a focus on understanding how neural circuits regulate eating and emotional behaviors such as fear, anxiety, and depression.We have purchased the RWD fiber photometry system and it is excellent in our experiments.l am satisfied with the data quality and accuracy, easy to set up and operate.

Department-of-NeuroscienceUniversity-of-Arizona

Dr. Haijiang Cai

Associate Professor Department of Neuroscience, University of Arizona

Strongly Recommend It for Non-programmers

We originally got a Demo fiber photometry set up from RWD for some free trials. Luckily, we collected very interesting pilot data for our grant application. Then we purchased one of their first-generation machines when we obtained the grant support. After more than two years' repeated tests, we are very satisfied with their system especially the analyzing program included. lt makes signal analysis and figure making much easier. We recently purchased one of their new-generation setups. lt works even better in terms of sensitivity. Strongly recommend this product if you are not good at Python or MATLAB.

Department of Psychology, Florida state University

Xiaobing Zhang

Associate Professor Department of Psychology, Florida state University

Our Customer

fiber-photometry-system-Typical-Customers

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